sickle cell anemia

pathology
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sickle cell anemia, hereditary disease that destroys red blood cells by causing them to take on a rigid “sickle” shape. The disease is characterized by many of the symptoms of chronic anemia (fatigue, pale skin, and shortness of breath) as well as susceptibility to infection, jaundice and other eye problems, delayed growth, and episodic crises of severe pain in the abdomen, bones, or muscles. Sickle cell anemia occurs mainly in persons of African descent. The disease also occurs in persons of Middle Eastern, Mediterranean, and Indian descent. The overall mortality rate of persons with the sickle cell trait is no ...(100 of 852 words)